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Neurophysiology of Severe Brain Damage

by V.L. Silakov

272 pages; quality trade paperback (softcover); Russian; catalogue #05-2753; ISBN 1-4120-7855-5; US$26.00, C$29.90, EUR21.36, £14.95

The book's main goal is to venture deep into the neurophysiological mechanisms underlying the compensatory phenomena that follow a massive structural and functional brain disintegration caused by severe brain trauma.


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About the Book About the Author Excerpts Catalogue Information

About the Book

Compensatory plasticity that follows a significant damage to the vast areas of the central nervous system is literally terra incognita in contemporary neurophysiology. The neurophysiological data on long-term compensatory plasticity and integrated detailed summary of the research in pathological processes developing after severe brain damage are presented in the book. The main objective of the book is to venture deep into the unknown of the compensatory phenomena that follow a massive structural and functional brain disintegration caused by a severe brain trauma in animals and humans. The book also contains an analysis of practically all Russian scientists' publications from the early classic period of the Highest Nervous Activity (Pavlov's term) until today as well as numerous references to the works in international physiology. Some specific principles have guided the direction of the author's theoretical and experimental approach to the problem of brain recovery. Learning mechanisms are the true pioneers on the way to recovery. This principle is the cornerstone in the foundation of effective studies of compensatory phenomena. Neuronal conditioning and recovery are intrinsically interconnected. Good recovery depends on the effective use of conditioning and the establishment of new intra- and intersystem temporary connections, which provide adequate adaptation to the environment.



About the Author

Valentine L. Silakov, M.D. is a professor of human and animal physiology. Born in St. Petersburg in Russia he obtained his medical degree from Medical State University of St. Petersburg. He has been the head of the Pavlov's Physiological Department at the Institute for Experimental Medicine and Laboratory of Primate Physiology in Pavlov's Physiological Institute of Russian Academy of Sciences. Being the author or coauthor of several books and over 150 scientific papers in the field of neurophysiology, particularly neurophysiology of severe brain damage he discovered general pattern of functional and structural transformations in sensory and motor brain systems providing effective compensation after hemidecortication.



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